Bio- Additive Manufacturing

3D Bioprinting of Polymer Scaffolds for Tissue Engineering : Fabrication and Characterization

Tissue engineering has emerged as a multidisciplinary strategy to address limitations in tissue reconstruction and regenerative medicine. These approaches synergistically combine macroporous biomaterial scaffolds, living cells, and bioactive molecules to promote tissue formation and functional restoration. Among scaffold fabrication techniques, additive manufacturing (3D printing) has gained prominence for its precise architectural control, high reproducibility, and ability to create complex, patient-specific geometries.

This project focuses on developing and characterizing 3D-printed polymeric biomaterials for tissue engineering. The primary objective is to design biomimetic scaffolds with controlled pore size, porosity, interconnectivity, vascularization, and cellular colonization. Advanced additive manufacturing will produce porous matrices tailored for bone, cartilage, and skin regeneration. Optimization will target mechanical properties, degradation kinetics, and surface bioactivity to balance structural stability and biological performance. Comprehensive morphological, mechanical, and biological characterizations will assess scaffold functionality and tissue integration potential.